Hypoxia-Inducible Factor-Proline Dioxygenases

Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA.

Also Known As:

Egl Nine Homolog 1 Protein; Egl Nine Homolog 2 Protein; Egl Nine Homolog 3 Protein; HIF Prolyl-4-Hydroxylase; HIF Prolyl-4-Hydroxylases; Hypoxia-Inducible Factor Prolyl Hydroxylase 1; Hypoxia-Inducible Factor Prolyl Hydroxylase 2; Hypoxia-Inducible Factor Prolyl Hydroxylase 3; Hypoxia-Inducible Factor-Proline Dioxygenase; Dioxygenase, Hypoxia-Inducible Factor-Proline; Dioxygenases, Hypoxia-Inducible Factor-Proline; Factor-Proline Dioxygenase, Hypoxia-Inducible; Factor-Proline Dioxygenases, Hypoxia-Inducible; HIF Prolyl 4 Hydroxylase; HIF Prolyl 4 Hydroxylases; Hypoxia Inducible Factor Proline Dioxygenase; Hypoxia Inducible Factor Proline Dioxygenases; Hypoxia Inducible Factor Prolyl Hydroxylase 1; Hypoxia Inducible Factor Prolyl Hydroxylase 2; Hypoxia Inducible Factor Prolyl Hydroxylase 3; Prolyl-4-Hydroxylase, HIF; Prolyl-4-Hydroxylases, HIF

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Oxidoreductases: 13899
    - Oxygenases: 336
      - Mixed Function Oxygenases: 2207
        Prolyl Hydroxylases: 1461
        Hypoxia-Inducible Factor-Proline Dioxygenases: 27
      - Dioxygenases: 513
        Prolyl Hydroxylases: 1461
        Hypoxia-Inducible Factor-Proline Dioxygenases: 27

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